What Is Cutthroat Trout Virus

Cutthroat trout virus CTV is a non-pathogenic ﬁsh virus belonging to the Hepeviridae family and it is distantly related to hepatitis E virus HEV. Only one serotype of the virus is known and classification is. Here we demonstrate that infections with the cutthroat trout virus CTV an avirulent salmonid virus Hedrick et al.

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Cutthroat Trout Virus

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The virus is currently recognized in only North America but has increasingly been identified in adult salmonid broodstock including rainbow trout Oncorhynchus mykiss cutthroat trout Oncorhynchus clarkii brown trout Salmo trutta and brook trout Salvelinus fontinalis in several western states of the United States.

What is cutthroat trout virus. However the cutthroat trout virus has yet to be associated. Help pages FAQs UniProtKB manual documents news archive and Biocuration projects. The CTV genome has a comparable size to the HEV genome and is organized in a similar way Batts et al 2011.

Here we report the development of an efficient cell culture system where CTV can consistently replicate to titers never observed before with a hepevirus. Raised in state hatcheries the trout were meant to bolster. We employed the cutthroat trout virus CTV a non-pathogenic fish virus with remarkable similarities to HEV as a potential surrogate for HEV and established an antiviral assay against this virus using the Chinook salmon embryo CHSE-214 cell line.

Cutthroat trout virus CTV is a non-pathogenic fish virus belonging to the Hepeviridae family and it is distantly related to hepatitis E virus HEV. Here we report the development of an efficient cell culture system where CTV can consistently replicate to titers never observed before with a hepevirus. CTV whose genome was first characterized by USGS researchers is being used in research into the human virus Hepatitis E.

Ribavirin and the respective trout interferon were found to efficiently inhibit CTV replication. Cutthroat trout virus CTV is a non-pathogenic fish virus belonging to the Hepeviridae family and it is distantly related to hepatitis E virus HEV. 14032016 Detailed Description Electron micrograph of the cutthroat trout virus CTV showing the small round virions of approximately 30 nanometers in diameter containing a single-stranded RNA genome.

Although this virus is of similar size and morphology as other hepeviruses it shares only approximately 1327 amino acid sequence identity with. Cutthroat Trout VirusTowards a Virus Model to Support Hepatitis E Research. Termed the cutthroat trout Oncorhynchus clarkii virus CTV the small round virus was not associated with disease but was subsequently found to be present in an increasing number of trout populations in the western.

1991 can create a resistant state among rainbow trout alevins to subsequent infections with IHNV. Beginning in 1988 the Chinook salmon embryo CHSE-214 cell line was used to isolate a novel virus from spawning adult trout in the state of California USA. Furthermore we demonstrate the longevity of this response and the resultant effect of prior CTV infec-.